695 Results for "

Macaranga sinensis (Baill.) Muell. Arg.

" in MedChemExpress (MCE) Product Catalog:
Products (695)

695 Results for "Macaranga sinensis (Baill.) Muell. Arg." in MCE Product Catalog:

64
64 Publications Verification
製品番号: HY-18234A
CAS 番号: 103476-89-7
Leupeptin hemisulfate is a broad-spectrum protease inhibitor. Leupeptin hemisulfate inhibits serine, cysteine and threonine proteases, and regulates autophagy. Leupeptin hemisulfate reduces the expression levels of LC3B, iNOS, Cox-2, Beclin-1 and the level of endopeptidases; increases the levels of p62, Arg 1, Msr 1 and Mrc 1; and blocks the upregulation of p-PTEN, p-NF-κB, p-PI3K, p-Akt, p-p38 and ERK1/2. Leupeptin hemisulfate inhibits NO, ROS, proinflammatory cytokines, the IFN-γ/IL-10 ratio, phagolysosome fusion, mammalian lysosomal hydrolase activity and SARS-CoV-2 replication; and reverses impaired autophagic flux. Leupeptin hemisulfate is applicable to research related to chronic inflammatory diseases, edema, skin tumorigenesis, COVID-19 and respiratory infections .
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20
20 Cited Publications
製品番号: HY-100742A
CAS 番号: 2003234-63-5
純度:  99.73%
(R)-GNE-140 is a potent inhibitor of lactate dehydrogenase (LDH) A, B and C, with IC50 values of 3, 5 and 5 nM against LDHA, LDHB, LDHC, respectively. (R)-GNE-140 blocks the conversion of pyruvate to lactate, reduces lactate production and histone lysine lactylation, and inhibits glycolysis. (R)-GNE-140 attenuates cardiac hypertrophy, alleviates PM2.5-induced pulmonary inflammation and fibrosis, blocks MRSA-induced Arg1 expression. (R)-GNE-140 is applicable to research related to pathological cardiac hypertrophy, pulmonary fibrosis, MRSA infection and pancreatic cancer .
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12
12 Cited Publications
製品番号: HY-101444A
CAS 番号: 100929-99-5
純度:  99.89%
別名: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
Target:  

Bacterial

研究分野:  

Infection

PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
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11
11 Cited Publications
製品番号: HY-P0019
CAS 番号: 66216-78-2
研究分野:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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11
11 Cited Publications
製品番号: HY-P0019A
CAS 番号: 2070009-61-7
研究分野:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
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10
10 Cited Publications
製品番号: HY-P0049
CAS 番号: 113-79-1
別名: Arg8-vasopressin; AVP
Target:  

Vasopressin Receptor

研究分野:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
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10
10 Cited Publications
製品番号: HY-W539944
CAS 番号: 129979-57-3
別名: Arg8-vasopressin acetate; AVP acetate
Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
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9
9 Cited Publications
製品番号: HY-12290
CAS 番号: 91037-65-9
純度:  99.93%
別名: RGDS peptide; Fibronectin tetrapeptide
Target:  

Integrin

研究分野:  

Inflammation/Immunology

Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
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7
7 Cited Publications
製品番号: HY-112885B
CAS 番号: 2250019-93-1
純度:  99.96%
別名: Nω-Hydroxy-nor-L-arginine monoacetate
nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
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7
7 Cited Publications
製品番号: HY-112885A
CAS 番号: 1140844-63-8
純度:  98.81%
別名: Nω-Hydroxy-nor-L-arginine acetate
nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
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7
7 Cited Publications
製品番号: HY-112885C
CAS 番号: 291758-32-2
純度:  98.85%
別名: Nω-Hydroxy-nor-L-arginine dihydrochloride
nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
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4
4 Cited Publications
製品番号: HY-N0691
CAS 番号: 7432-28-2
別名: Schizandrin; Schizandrol; Schizandrol-A
Schisandrin (Schizandrin), a dibenzocyclooctadiene lignan, is isolated from the fruit of Schisandra chinensis Baill. Schisandrin exhibits antioxidant, hepatoprotective, anti-cancer and anti-inflammatory activities. Schisandrin also can reverses memory impairment in rats .
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3
3 Cited Publications
製品番号: HY-P0074A
CAS 番号: 157009-81-9
別名: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
Target:  

Integrin

研究分野:  

Cardiovascular Disease

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
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3
3 Cited Publications
製品番号: HY-P0074
CAS 番号: 67869-62-9
別名: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

研究分野:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
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3
3 Cited Publications
製品番号: HY-N0708
CAS 番号: 121-34-6
Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects .
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2
2 Cited Publications
製品番号: HY-134434
CAS 番号: 136132-67-7
純度:  99.79%
研究分野:  

Others

Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .
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2
2 Cited Publications
製品番号: HY-112862
CAS 番号: 301351-95-1
純度:  ≥98.0%
研究分野:  

Infection

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
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2
2 Cited Publications
製品番号: HY-P2300
CAS 番号: 862772-11-0
別名: Cyclo(RGDfC)
Target:  

Integrin

研究分野:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .
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2
2 Cited Publications
製品番号: HY-P2300A
別名: Cyclo(RGDfC) TFA
Target:  

Integrin

研究分野:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA can be used in the research of tumors .
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2
2 Cited Publications
製品番号: HY-W016781
CAS 番号: 157-06-2
別名: H-D-Arg-OH
D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research . .
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